In the digital healthcare era, it is utmost important to harness medical information scattered across healthcare institutions to support in-depth data analysis. However, the boundaries of cyberinfrastructure of healthcare providers place obstacles on data sharing. In this position paper, we firstly identify the challenges of medical data sharing and management. Then we introduce the background and give a brief survey on the state-of-the-art. Finally, we conclude the paper by discussing a few possible research directions to cope with the challenges in current medical information sharing.